The American River borders the southern boundary of Nepenthe, south of University Avenue. The American River Parkway is county-owned and has miles of free walking and biking trails. The levee, which protects the neighborhood from flooding, is maintained by the U.S. Army Corps of Engineers.
The American River Bike and horse trails are easily accessible to Nepenthe residents. The trail is set amidst lush foliage and fields with native wildlife and birds and forms a perimeter around Nepenthe. Cyclists, walkers, and equestrians can enjoy 33 miles of trail from Old Sacramento to Folsom.